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Volume 8, Issue 4 / 2018 Available Online

Reviews
The Role of TMEM230 Gene in Parkinson’s DiseaseOpen Access
Deng, Hao | Fan, Kuan | Jankovic, Joseph

Modeling Parkinson’s Disease Using Patient-specific Induced Pluripotent Stem CellsOpen Access
Li, Hong | Jiang, Houbo | Zhang, Boyang | Feng, Jian

Research Articles
Parkinson MattersOpen Access (View Press Release Here)
Darweesh, Sirwan K.L. | Raphael, Karen G. | Brundin, Patrik | Matthews, Helen | Wyse, Richard K. | Chen, Honglei | Bloem, Bastiaan R.

The European Physiotherapy Guideline for Parkinson’s Disease: Implications for Neurologists
Domingos, Josefa | Keus, Samyra H.J. | Dean, John | de Vries, Nienke M. | Ferreira, Joaquim J. | Bloem, Bastiaan R.

Investigating Voice as a Biomarker for Leucine-Rich Repeat Kinase 2-Associated Parkinson’s Disease
Arora, Siddharth | Visanji, Naomi P. | Mestre, Tiago A. | Tsanas, Athanasios | AlDakheel, Amaal | Connolly, Barbara S. | Gasca-Salas, Carmen | Kern, Drew S. | Jain, Jennifer | Slow, Elizabeth J. | Faust-Socher, Achinoam | Lang, Anthony E. | Little, Max A. | Marras, Connie

Multimorbidity Predicts Quality of Life but not Motor Severity in Early Parkinson’s Disease
Gravell, Rhys | Duncan, Gordon W. | Khoo, Tien K. | Burn, David J. | Sayer, Avan A. | Barker, Roger A. | Lawson, Rachael Ashleigh | Yarnall, Alison Jane

Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)Open Access
Chahine, Lana M. | Beach, Thomas G. | Seedorff, Nicholas | Caspell-Garcia, Chelsea | Coffey, Christopher S. | Brumm, Michael | Adler, Charles H. | Serrano, Geidy E. | Linder, Carly | Mosovsky, Sherri | Foroud, Tatiana | Riss, Holly | Ecklund, Dixie | Seibyl, John | Jennings, Danna | Arnedo, Vanessa | Riley, Lindsey | Dave, K.D. | Mollenhauer, Brit | on behalf of the Systemic sSynuclein Sampling study

Objective Arm Swing Analysis in Early-Stage Parkinson’s Disease Using an RGB-D Camera (Kinect)Open Access
Ospina, Beatriz Muñoz | Chaparro, Jaime Andrés Valderrrama | Paredes, Juan David Arango | Pino, Yor Jaggy Castaño | Navarro, Andrés | Orozco, Jorge Luis

Weight Loss in Parkinson’s Disease: No Evidence for Role of Small Intestinal Bacterial Overgrowth
DiBaise, John K. | Crowell, Michael D. | Driver-Dunckley, Erika | Mehta, Shyamal H. | Hoffman-Snyder, Charlene | Lin, Tanya | Adler, Charles H.

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In the News

Read all the recent JPD press releases

JPD news 4

Three news releases issued in September, featuring research published in recent issues of JPD, have resulted in substantial press coverage.

The first of these relates to the open access article Parkinson Matters – published in this new issue – which is a call to action to improve patient care.

In the paper, experts propose ways to address the rapidly rising number of deaths from Parkinson’s disease and related disorders and improve the end of life care of Parkinson patients. Reviewing the report, a team of international experts led by Prof. Bastiaan R. Bloem, explore the deeper relevance of the numbers and trends. “There are several possible explanations for the increase in mortality associated with Parkinson’s disease. It is certainly in keeping with other recent reports that point to a striking rise in the incidence of new patients with Parkinson’s disease in the general population," comments Prof. Bloem.

To read all the press releases in full, visit:

▪ Parkinson Matters: A Call to Action to Improve Patient Care
▪ Eradicating Helicobacter Pylori Infections May Be a Key Treatment for PD
▪ Optimizing Dopaminergic Treatment Improves Non-Motor Symptoms in Severe PD
Parkinson Matters: A Call to Action to Improve Patient Care
Eradicating Helicobacter Pylori Infections May Be a Key Treatment for PD
Optimizing Dopaminergic Treatment Improves Non-Motor Symptoms in Severe PD

To keep up to date with the latest news, check the JPD website and the IOS Press website.

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Most Read JPD Articles in September 2018

Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in RodentsOpen Access (Research Article in Vol.8, Iss.2, 2018)
Polinski, Nicole K. | Volpicelli-Daley, Laura A. | Sortwell, Caryl E. | Luk, Kelvin C. | Cremades, Nunilo | Gottler, Lindsey M. | Froula, Jessica | Duffy, Megan F. | Lee, Virginia M. Y. | Martinez, Terina N. | Dave, Kuldip D.

Modeling Parkinson’s Disease Using Patient-specific Induced Pluripotent Stem CellsOpen Access (Review Article in Vol.8, Iss.4, 2018)
Li, Hong | Jiang, Houbo | Zhang, Boyang | Feng, Jian

Stomaching the Possibility of a Pathogenic Role for Helicobacter Pylori in Parkinson’s DiseaseOpen Access (Review Article in Vol.8, Iss.3, 2018) (View Press Release Here)
McGee, David J. | Lu, Xiao-Hong | Disbrow, Elizabeth A.

Precision Medicine in Parkinson’s Disease – Exploring Patient-Initiated Self-TrackingOpen Access (Research Article in Vol.8, Iss.2, 2018)
Riggare, Sara | Hägglund, Maria

Parkinson MattersOpen Access (Research Article in Vol.8, Iss.4, 2018) (View Press Release Here)
Darweesh, Sirwan K.L. | Raphael, Karen G. | Brundin, Patrik | Matthews, Helen | Wyse, Richard K. | Chen, Honglei | Bloem, Bastiaan R.

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Collection of Quarterly Parkinson's Webinars

Watch Video of September Webinar & Save the Date for December!

JPD is working in partnership with The Cure Parkinson’s Trust (CPT) and Parkinson’s Movement to concisely capture a snapshot of the science of PD and translate it to deliver better understanding for all. Linked to this initiative, a series of Quarterly Parkinson's Webinars was launched to bring the discussion of specific research topics into the open, so the whole process of rating research will become even more transparent.

The latest webinar, held during September, was the second in the series and it was a great success. A video of the webinar can be viewed by clicking on the image below or online here. We encourage you to allocate some time to view this interesting discussion, which was based around the paper by Prof. Per Borghammer entitled: “How Does Parkinson’s Disease Begin? Perspectives on Neuroanatomical Pathways, Prions, and Histology”.

Next Parkinson Webinar: December 5, 2018

The next webinar will take place on Dec 5 (12.30 ET, 18.30 CET) and details will be announced soon. Be sure to check back to our website for more details, or follow JPD's Facebook and Twitter streams to be kept up to speed and to sign up for your spot at the webinar!

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Sign Ups & Social Media

If you know any colleagues and fellow researchers who are not signed up to receive the newsletter, we invite you to share this mailing with them. They can sign up at: tiny.cc/JPDsignup

Also, if you are not already, be sure to follow us on Twitter and find us on Facebook for news related to JPD and PD research.

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