Review Articles Aberrant Neuronal Cell Cycle Re-Entry: The Pathological Confluence of Alzheimer’s Disease and Brain Insulin Resistance, and Its Relation to Cancer Koseoglu, Mehmet Murat | Norambuena, Andrés | Sharlow, Elizabeth R. | Lazo, John S. | Bloom, George S. Tau Abnormalities and the Potential Therapy in Alzheimer’s Disease Almansoub, Hasan A.M.M. | Tang, Hui | Wu, Ying | Wang, Ding-Qi | Mahaman, Yacoubou Abdoul Razak | Wei, Na | Almansob, Yusra A. M. | He, Wei | Liu, Dan Sex Differences in Alzheimer’s Disease: Where Do We Stand? Medeiros, André de Macêdo | Silva, Regina Helena Other Content Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies Rizzo, Giovanni | De Blasi, Roberto | Capozzo, Rosa | Tortelli, Rosanna | Barulli, Maria Rosaria | Liguori, Rocco | Grasso, Daniela | Logroscino, Giancarlo Blood Glucose Levels May Exacerbate Executive Function Deficits in Older Adults with Cognitive Impairment Pappas, Colleen | Small, Brent J. | Andel, Ross | Laczó, Jan | Parizkova, Martina | Ondrej, Lerch | Hort, Jakub Subtypes Based on Neuropsychological Performance Predict Incident Dementia: Findings from the Rush Memory and Aging Project Zammit, Andrea R. | Muniz-Terrera, Graciela | Katz, Mindy J. | Hall, Charles B. | Ezzati, Ali | Bennett, David A. | Lipton, Richard B. Astrocyte- and Microglia-Specific Mitochondrial DNA Deletions Levels in Sporadic Alzheimer’s Disease Strobel, Sabrina | Grünblatt, Edna | Heinsen, Helmut | Riederer, Peter | Espach, Thomas | Meder, Michael | Monoranu, Camelia-Maria A Comparison of Partial Volume Correction Techniques for Measuring Change in Serial Amyloid PET SUVR – Open Access Schwarz, Christopher G. | Gunter, Jeffrey L. | Lowe, Val J. | Weigand, Stephen | Vemuri, Prashanthi | Senjem, Matthew L. | Petersen, Ronald C. | Knopman, David S. | Jack Jr, Clifford R. Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study Hvidsten, Lara | Engedal, Knut | Selbæk, Geir | Wyller, Torgeir Bruun | Benth, Jūratė Šaltytė | Kersten, Hege Next Generation Sequencing Analysis in Early Onset Dementia Patients – Open Access Bonvicini, Cristian | Scassellati, Catia | Benussi, Luisa | Di Maria, Emilio | Maj, Carlo | Ciani, Miriam | Fostinelli, Silvia | Mega, Anna | Bocchetta, Martina | Lanzi, Gaetana | Giacopuzzi, Edoardo | Ferraboli, Sergio | Pievani, Michela | Fedi, Virginia | Defanti, Carlo Alberto | Giliani, Silvia | Frisoni, Giovanni Battista | Ghidoni, Roberta | Gennarelli, Massimo Vital Exhaustion and Incidence of Dementia: Results from the Copenhagen City Heart Study – Open Access Islamoska, Sabrina | Ishtiak-Ahmed, Kazi | Hansen, Åse Marie | Grynderup, Matias Brødsgaard | Mortensen, Erik Lykke | Garde, Anne Helene | Gyntelberg, Finn | Prescott, Eva Irene Bossano | Török, Eszter | Waldemar, Gunhild | Nabe-Nielsen, Kirsten | Four recent blog posts available! | Be sure to visit the Editors' Blog section of the JAD website to discover recent content: Recent Advances in the Field of 3D Modelling for Neurodegeneration by Silvia Bolognin In the last few years, we have witnessed a tremendous advancement in cell culturing methods. The scene has been dominated by the optimization of 3D in vitro models either in the form of dissociated neuronal cultures or of the so-called organoids. The attempt of introducing new methods responds to the difficulty of capturing the multifactorial nature of diseases such as Alzheimer’s and Parkinson’s diseases in conventional models. Prion Protein and Alzheimer's Disease by Saima Zafar Alzheimer's disease is the most prevalent form of dementia with large impact on population over the age of 65 years. The most distinctive symptomatic phase during the disease is the decline of the cognition with the loss of synapses. In recent years, there is debate on cellular form of PrP and its role in AD as a negative key player or protective modulator in-conjugation with amyloid-β oligomers. What Does Music Therapy Look Like for Persons with AD? by Amy Clements-Cortes This blog is a follow-up to the one I published in August 2017, titled “Music Experiences for Persons with AD”. In this piece, I am focusing on one of the experiences: Music Therapy. As an inexpensive, evidence-based, and non-pharmacological treatment, music therapy should highly be considered in the total care package for persons living with AD. Alzheimer’s Disease, the Sweet Trail to Neuroprotection by Stefano Sensi In Alzheimer’s disease, we are gaining great ground in the field of early diagnosis, but disease-modifying drugs are still missing. While many studies have been focused on the pathogenic role of amyloid-β dysmetabolism, recent preclinical and clinical findings revealed a more complex picture. In AD, we need to embrace a complex view of the disease state as a condition resulting from the converging failure of health-controlling systems and networks. | Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides Cam, Morgane | Durieu, Emilie | Bodin, Marion | Manousopoulou, Antigoni | Koslowski, Svenja | Vasylieva, Natalia | Barnych, Bogdan | Hammock, Bruce D. | Bohl, Bettina | Koch, Philipp | Omori, Chiori | Yamamoto, Kazuo | et al. Odor Identification Ability Predicts PET Amyloid Status and Memory Decline in Older Adults Kreisl, William Charles | Jin, Peng | Lee, Seonjoo | Dayan, Ezra R. | Vallabhajosula, Shankar | Pelton, Gregory | Luchsinger, José A. | Pradhaban, Gnanavalli | Devanand, D.P. Neuropsychiatric Symptoms and the Diagnostic Stability of Mild Cognitive Impairment Sugarman, Michael A. | Alosco, Michael L. | Tripodis, Yorghos | Steinberg, Eric G. | Stern, Robert A. Plasma Amyloid-β Correlates with Cerebrospinal Fluid Aβ42 in Alzheimer’s Disease Teunissen, Charlotte E. | Chiu, Ming-Jang | Yang, Che-Chuan | Yang, Shieh-Yueh | Scheltens, Philip | Zetterberg, Henrik | Blennow, Kaj Cardiorespiratory Fitness and Cognitive Function are Positively Related Among Participants with Mild and Subjective Cognitive Impairment Stuckenschneider, Tim | Askew, Christopher David | Rüdiger, Stefanie | Polidori, Maria Cristina | Abeln, Vera | Vogt, Tobias | Krome, Andreas | Olde Rikkert, Marcel | Lawlor, Brian | Schneider, Stefan | on behalf of the NeuroExercise Study Group Herpes Simplex Virus, APOEɛ4, and Cognitive Decline in Old Age: Results from the Betula Cohort Study Lövheim, Hugo | Norman, Tove | Weidung, Bodil | Olsson, Jan | Josefsson, Maria | Adolfsson, Rolf | Nyberg, Lars | Elgh, Fredrik | Most Read JAD Articles in 2018 Via the IOS Press content website Alzheimer’s Disease Can Be Spared by Nonsteroidal Anti-Inflammatory Drugs – Open Access (Review Article in Vol.62, Iss.3, 2018) McGeer, Patrick L. | Guo, Jian Ping | Lee, Moonhee | Kennedy, Krista | McGeer, Edith G. Is Caffeine a Cognitive Enhancer? – Open Access (Review Article in Vol.20, Iss.s1, 2010) Nehlig, Astrid Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer’s Disease: A Randomized Controlled – Open Access (Research Article in Vol.50, Iss.2, 2016) Hoffmann, Kristine | Sobol, Nanna A. | Frederiksen, Kristian S. | Beyer, Nina | Vogel, Asmus | Vestergaard, Karsten | Brændgaard, Hans | Gottrup, Hanne | Lolk, Annette | Wermuth, Lene | Jacobsen, Søren | Laugesen, Lars P. | Gergelyffy, Robert G. | Høgh, Peter | Bjerregaard, Eva | Andersen, Birgitte B. | Siersma, Volkert | Johannsen, Peter | Cotman, Carl W. | Waldemar, Gunhild | Hasselbalch, Steen G. Microbes and Alzheimer’s Disease – Open Access (Editorial in Vol.51, Iss.4, 2016) Itzhaki, Ruth F. | Lathe, Richard | Balin, Brian J. | Ball, Melvyn J. | Bearer, Elaine L. | Braak, Heiko | Bullido, Maria J. | Carter, Chris | Clerici, Mario | Cosby, S. Louise | Del Tredici, Kelly | Field, Hugh | Fulop, Tamas | Grassi, Claudio | Griffin, W. Sue T. | et al. How Does Exercise Reduce the Rate of Age-Associated Cognitive Decline? A Review of Potential Mechanisms – Openly Available (Review Article in Vol.55, Iss.1, 2016; winner of the 2018 Alzheimer Award) Kennedy, Greg | Hardman, Roy J. | Macpherson, Helen | Scholey, Andrew B. | Pipingas, Andrew | Please share the JAD Newsletter with your colleagues! | If you know any colleagues and fellow researchers who are not signed up to receive the JAD newsletter, we invite you to share this mailing with them. They can sign up at: tiny.cc/JADsignup We hope news of our open access Journal of Alzheimer's Disease Reports will also be of interest? Sign up here to be sure of receiving the quarterly JADR mailing direct to your inbox! Also, if you are not already, be sure to follow us on Twitter and find us on Facebook for news related to JAD and AD research. Be part of the discussion! | |