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JPD 11

Indexed in: PubMed/MEDLINE Web of Science Scopus

Volume 9, Issue 4 / 2019 Available Online

Functional Connectivity Signatures of Parkinson’s DiseaseOpen Access
Tessitore, Alessandro | Cirillo, Mario | De Micco, Rosa

Detecting Apathy in Individuals with Parkinson’s Disease: A Systematic Review
Mele, Bria | Merrikh, Daria | Ismail, Zahinoor | Goodarzi, Zahra

Predicting Progression in Parkinson’s Disease Using Baseline and 1-Year Change MeasuresOpen Access
Chahine, Lana M. | Siderowf, Andrew | Barnes, Janel | Seedorff, Nicholas | Caspell-Garcia, Chelsea | Simuni, Tanya | Coffey, Christopher S. | Galasko, Douglas | Mollenhauer, Brit | et al.

Diagnostic Potential of Multimodal MRI Markers in Atypical Parkinsonian Disorders
Seki, Morinobu | Seppi, Klaus | Mueller, Christoph | Potrusil, Thomas | Goebel, Georg | Reiter, Eva | Nocker, Michael | Kremser, Christian | Wildauer, Matthias | Schocke, Michael | et al.

Putaminal Dopamine Turnover in de novo Parkinson’s Disease Predicts Later Neuropsychiatric Fluctuations but Not Other Major Health Outcomes
Löhle, Matthias | Hermann, Wiebke | Hausbrand, Denise | Wolz, Martin | Mende, Julia | Beuthien-Baumann, Bettina | Oehme, Liane | van den Hoff, Jörg | Kotzerke, Jörg | et al.

Plasma IL-6 and IL-17A Correlate with Severity of Motor and Non-Motor Symptoms in Parkinson’s DiseaseOpen Access
Green, Holly F. | Khosousi, Shervin | Svenningsson, Per

Fecal and Blood Microbial 16s rRNA Gene Alterations in Chinese Patients with Multiple System Atrophy and Its SubtypesOpen Access
Du, Juanjuan | Huang, Pei | Qian, Yiwei | Yang, Xiaodong | Cui, Shishuang | Lin, Yiqi | Gao, Chao | Zhang, Pingchen | He, Yixi | Xiao, Qin | Chen, Shengdi

Chronological View of Peak and Diphasic Dyskinesia, Wearing Off and Freezing of Gait in Parkinson’s Disease
Kim, Young Eun | Jeon, Beomseok | Yun, Ji Young | Yang, Hui-Jun | Kim, Han-Joon

How to Annotate Freezing of Gait from Video: A Standardized Method Using Open-Source Software
Gilat, Moran

JPD Blog Updates

Benjamin Stecher's Recent Posts

We share the recent posts that have been published in the Tomorrow Edition Extracts section of the JPD website. As an introduction, here is a note from our blog author Benjamin Stecher: "I started this journey with no background in biomedical science, let alone Parkinson's research. But I have been lucky enough to get to know a number of great thinkers who have guided me as I have tried to navigate these dark and mysterious worlds. I would like to pay special tribute to the following three individuals who have each shined a light for me at various points along the way and had an enormous impact on the way I think about this disease." To read the recent posts, click the links below.

Interview with Clinical Research Scientist Prof. Karen RaphaelOpenly Available (published October 2019) | Discussion that highlights some common misconceptions about clinical trials

Interview With Research Scientist And Communicator Dr. Simon StottOpenly Available (published September 2019) | Discussion about PD from research and communication perspectives

Interview with Neuromodulation Expert Dr. Alfonso FasanoOpenly Available (published August 2019) | Discussion covering brain machine interfaces and deep brain stimulation

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Collection of Quarterly Parkinson's Webinars

Watch the October Webinar Recording!

The latest instalment of our quarterly Parkinson’s webinar series, organized in partnership with the Cure Parkinson's Trust and Parkinson’s Movement, took place on October 2, 2019 and it was a full house. The topic was Dyskinesia in Parkinson’s.

The eminent panel, once again chaired by Van Andel Institute’s Patrik Brundin, comprised clinical expertise from Ray Chaudhuri (Kings College, London, UK) and Robert Hauser (University of South Florida, USA), pre-clinical insights from Angela Cenci Nilsson (Lund University, Sweden), and patient views from Martin Taylor, founder of the Parkinson’s Research Interest Group on Facebook (UK).

The discussion focused on publications in the field, in particular the recent open access JPD paper "Clinical Trials Hilghights: Dyskinesia" by Kevin McFarthing, Neha Prakash, and Tanya Simuni. The recording of the online webinar is now available. Recordings of all previous webinars can be accessed here.

Check our website soon for details of the December webinar (date & topic TBC)

To watch the recording of the October webinar, click the visual

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In the News

Press releases relating to recent JPD content

Fatigue in Parkinson’s Disease Is Associated with Lower Diastolic Blood Pressure

Fatigue is a common debilitating symptom in Parkinson's disease (PD). A novel research study has found that fatigue symptoms in PD are associated with small but persistent reductions in diastolic blood pressure (DBP) throughout the day. "The majority of people with PD consider fatigue, defined as diminished energy levels or increased perception of effort that is disproportionate to attempted activities, to be one of their three biggest symptomatic concerns. But despite its high prevalence and disabling nature, we know relatively little about its underlying causes," explained lead investigator Vikas Kotagal, MD, MS. "Understanding the biological basis for fatigue in PD is a key step towards designing effective treatments. This is an important goal for the field of PD clinical research."

Open Access Research Article:
Fatigue in Parkinson's Disease Associates with Lower Ambulatory Diastolic Blood Pressure

Read the full press release here


How and Why Does Parkinson’s Disease Affect Women and Men Differently?

There is growing evidence that Parkinson's disease (PD) affects women and men differently. In this insightful review, scientists present the most recent knowledge about these sex-related differences and highlight the significance of estrogens, which play an important role in the sex differences in PD. “It is becoming increasingly evident that PD differs in women and men,” explained lead author Fabio Blandini. “Recent research findings suggest that biological sex also impacts on disease risk factors and, potentially, on molecular mechanisms involved in the pathogenesis of PD.”

Open Access Revew Article:
Parkinson's Disease in Women and Men: What's the Difference?

Read the full press release here

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Most Read JPD Articles in September 2019

Most viewed JPD content via the IOS Press content website: all articles published in 2019

Parkinson’s Disease in Women and Men: What’s the Difference?Open Access (Review Article in Vol.9, Iss.3, 2019; View Press Release)
Cerri, Silvia | Mus, Liudmila | Blandini, Fabio

Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systematic ReviewOpen Access (Review Article in pre-press, 2019)
Boertien, Jeffrey M. | Pereira, Pedro A.B. | Aho, Velma T.E. | Scheperjans, Filip

Extended Treatment with Glial Cell Line-Derived Neurotrophic Factor in Parkinson’s DiseaseOpen Access (Research Article in Vol.9, Iss.2, 2019; View Press Release)
Whone, Alan L. | Boca, Mihaela | Luz, Matthias | Woolley, Max | Mooney, Lucy | Dharia, Sonali | Broadfoot, Jack | Cronin, David | Schroers, Christian | Barua, Neil U. | Longpre, Lara | et al.

Brain-First versus Gut-First Parkinson’s Disease: A HypothesisOpen Access (Review Article in pre-press, 2019)
Borghammer, Per | Van Den Berge, Nathalie

Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systematic ReviewOpen Access (Review Article in pre-press, 2019)
Boertien, Jeffrey M. | Pereira, Pedro A.B. | Aho, Velma T.E. | Scheperjans, Filip

Coming soon: Our special issue on the gut–brain axis in Parkinson’s disease!

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Also of Interest? JAD Special Issue on Gait Disorders

All articles in this special issue freely available until end of October! View content | View mailing

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