Introducing New Section: Clinical Trials Highlights Section Editors: Kevin McFarthing and Tanya Simuni |  Indexed in: PubMed/MEDLINE Scopus | INTRODUCING CLINICAL TRIALS HIGHLIGHTS: The objective of the new Clinical Trial Highlights section is to raise awareness of the clinical trial landscape in Parkinson’s, promoting discussion and progress in the conduct and outcome of studies. Read the full introduction in this issue here, and the first content at: Phase III Study in Spotlight – Openly Available | Summary of one study of isradipine as a disease modifying agent in patients with early PD Targeting Alpha-Synuclein – Openly Available | Summaries of eight studies of alpha-synuclein for immunotherapies and mechanistic targets | Reviews
The Amphetamine Induced Rotation Test: A Re-Assessment of Its Use as a Tool to Monitor Motor Impairment and Functional Recovery in Rodent Models of Parkinson’s Disease – Open Access
Björklund, Anders | Dunnett, Stephen B. A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein – Open Access (view press release here)
Merchant, Kalpana M. | Cedarbaum, Jesse M. | Brundin, Patrik | Dave, Kuldip D. | Eberling, Jamie | Espay, Alberto J. | et al. Research Articles
A Systematic Review and Case Series of Ziprasidone for Psychosis in Parkinson’s Disease – Open Access
Younce, John R. | Davis, Albert A. | Black, Kevin J. The Effect of Different Exercise Modes on Domain-Specific Cognitive Function in Patients Suffering from Parkinson’s Disease: A Systematic Review of Randomized Controlled Trials
Stuckenschneider, Tim | Askew, Christopher D. | Menêses, Annelise L. | Baake, Ricarda | Weber, Jan | Schneider, Stefan HSP90 and Its Novel Co-Chaperones, SGT1 and CHP-1, in Brain of Patients with Parkinson’s Disease and Dementia with Lewy Bodies – Open Access
Bohush, Anastasiia | Niewiadomska, Grażyna | Weis, Serge | Filipek, Anna Haplotype Analysis on the Relationship of the DNAJC6 Gene with Early-Onset Parkinson’s Disease Risk in a Chinese Population
Shen, Ting | Zhao, Shuai | Jiang, Yasi | Pu, Jiali | Lai, Hsin-Yi | Yan, Yaping | et al. Single Inflammatory Trigger Leads to Neuroinflammation in LRRK2 Rodent Model without Degeneration of Dopaminergic Neurons
Schildt, Anna | Walker, Matthew D. | Dinelle, Katherine | Miao, Qing | Schulzer, Michael | et al. Other Content
How I Examine My Patient: The Shaking Shoelace – Open Access
Bloem, Bastiaan R. | Helmich, Rick C. | Tilanus, Tiane | van de Warrenburg, Bart P. | | Read all the recent JPD press releases | Most Read JPD Articles in January 2019 Listing articles published only in 2018 and 2019 so you can read the most popular recent content The Emerging Evidence of the Parkinson Pandemic – Open Access (Review Article in Vol.8, Iss.s1, 2018)
Dorsey, E. Ray | Sherer, Todd | Okun, Michael S. | Bloem, Bastiaan R. A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein – Open Access (Review Article in Vol.9, Iss.1, 2019)
Merchant, Kalpana M. | Cedarbaum, Jesse M. | Brundin, Patrik | Dave, Kuldip D. | Eberling, Jamie | Espay, Alberto J. | et al. Parkinson Diseases in the 2020s and Beyond: Replacing Clinico-Pathologic Convergence With Systems Biology Divergence – Open Access (Review Article in Vol.8, Iss.s1, 2018)
Espay, Alberto J. | Lang, Anthony E. The Search for Environmental Causes of Parkinson’s Disease: Moving Forward – Open Access (Review Article in Vol.8, Iss.s1, 2018)
Chen, Honglei | Ritz, Beate The Times They Are a-Changin': Parkinson’s Disease 20 Years from Now – Open Access (Introduction in Vol.8, Iss.s1, 2018)
Brundin, Patrik | Bloem, Bastiaan R. | Next Webinar: March 6, 2019! | The next instalment of our quarterly Parkinson’s webinar series, organized in partnership with the Cure Parkinson's Trust and Parkinson’s Movement, will take place on March 6, 2019. Recordings of all previous webinars can be accessed here. The discussion of the upcoming webinar will focus on: Sleep and Parkinson's Disease. Led by Professor Patrick Brundin, fellow panelists will include Michele Hu, Soania Mathur and Aleksandar Videnovic. The discussion will also cover this paper about the sleep–wake cycle. The online webinar is now open for registration. It is free to attend, though spaces are limited, so we urge you to book your place now to avoid disappointment. | March 26–31, 2019 | Lisbon, Portugal The upcoming AD/PD conference takes place in Lisbon, Portugal in March. Multidisciplinary researchers from around the world will present cutting-edge research and new treatments for Alzheimer's, Parkinson's and related neurodegenerative diseases. Registration savings are available until March 12 via the event website. | April 4–7, 2019 | Madrid, Spain The 13th World Congress on Controversies in Neurology (CONy) will take place in Madrid, Spain in April. It will provide a platform for international experts to discuss and compare experiences, thus closing the gap between the expansion of knowledge and its dissemination and use. Early registration savings are available until February 20 via the event website. | June 4–7, 2019 | Kyoto, Japan WPC 2019 will take place in Kyoto, Japan in June. It will showcase important developments in the world of PD, bringing together the full spectrum of those who serve the Parkinson’s community and those who live with PD. Discover more at the WPC 2019 blog. Early registration savings are available until February 27 via the event website. | JPD information will be available to delegates at all these meetings: we encourage delegates to consider submitting research to the journal and joining our quarterly webinars. | Rapidly expanding knowledge and technical possibilities may impact stem cell-based therapies for cell replacement in Parkinson’s disease, as outlined in the recent open access JPD review article "Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies" by Henchcliffe and Parmar. With this in mind, we introduce a new journal from the publishers of JPD. StemJournal is an open access forum for innovative scientific contributions from the many fields of research on stem cells. The launch of this new peer-reviewed journal for the stem cell community has an ultimate aim: to keep pace with developments in this burgeoning field and to lower the barrier to publishing truly integrative biomedical research on stem cells. Submissions are now welcome via the journal's website: stemjnl.org. | |
