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Please feel free forward to fellow researchers and share the news of our journal

Dear Colleague,

We are delighted to announce the publication of Volume 4, Number 1 of Bladder Cancer (BLC). The full contents are freely available online, and can be browsed in full below.

This issue hosts an outstanding selection of articles, including three comprehensive review articles covering the immune response to neoadjuvant chemotherapy, insights into DNA damage response and repair genes, and recent advances in circulating tumor DNA profiling techniques for bladder cancer.

The new issue is also the first one as the official journal of BCAN – keep reading for more details.


As the result of a new partnership announced last month, Bladder Cancer is now the official journal of the Bladder Cancer Advocacy Network (BCAN). Both organisations will combine resources to support a readily accessible information platform to serve the bladder cancer research and clinical practice communities.

The journal is dedicated to providing an open forum for publishing original peer-reviewed research in basic science, translational research and clinical medicine that will improve the fundamental understanding of bladder cancer and lead to more effective treatment of tumors of the bladder and upper urinary tract and improved patient outcomes.

BCAN is committed to supporting bladder cancer research and has cultivated a strong partnership with the leading members of the bladder cancer medical community to encourage collaboration among all the parties dedicated to the study of bladder cancer and its prevention, diagnosis and treatment. For news on BCAN's 2018 research grant programs, see below.


Call for Papers

As a member of our research community, we would like to invite you to contribute your own research articles to Bladder Cancer, which offers contributing authors many benefits:

• First class Editorial Board
• Rigorous peer review and speedy manuscript processing
• Rapid online publication (pre-print) on acceptance
• Articles are currently published Open Access with no article processing fee

Submit your manuscript electronically
View detailed Instructions to Authors
Aims and Scope

We look forward to working with you.

Best wishes,


Seth P. Lerner
Scott Department of Urology
Baylor College of Medicine
Houston, Texas, USA

Dan Theodorescu
University of Colorado Cancer Center
Aurora, Colorado, USA


All articles are freely available to all readers

Review: Immune Responses to Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer
Sherif, Amir | Winerdal, Malin | Winqvist, Ola

Review: Molecular and Clinical Insights into the Role and Significance of Mutated DNA Repair Genes in Bladder Cancer
Abbosh, Philip H. | Plimack, Elizabeth R.

Review: Liquid Biopsy-Analysis of Circulating Tumor DNA (ctDNA) in Bladder Cancer
Todenhöfer, Tilman | Struss, Werner J. | Seiler, Roland | Wyatt, Alexander William | Black, Peter C.

Role of Radical Cystectomy in Non-Organ Confined Bladder Cancer: A Systematic Review
Li, Roger | Metcalfe, Michael | Kukreja, Janet | Navai, Neema

Toward Personalised Liquid Biopsies for Urothelial Carcinoma: Characterisation of ddPCR and Urinary cfDNA for the Detection of the TERT 228 G>A/T Mutation
Russo, Ilaria J. | Ju, Yongwon | Gordon, Naheema S. | Zeegers, Maurice P. | Cheng, K.K. | James, Nicholas D. | Bryan, Richard T. | Ward, Douglas G.

Peri-Operative Chemotherapy for Bladder Cancer: A Survey of Providers to Determine Barriers and Enablers
Walker, Melanie | Doiron, R. Christopher | French, Simon D. | Brennan, Kelly | Feldman-Stewart, Deb | Siemens, D. Robert | Mackillop, William J. | Booth, Christopher M.

Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7
Bolenz, Christian | Knauf, Daniel | John, Axel | Erben, Philipp | Steidler, Annette | Schneider, Stefan W. | Günes, Cagatay | Gorzelanny, Christian

Molecular Correlates of In Vitro Responses to Dacomitinib and Afatinib in Bladder Cancer
Tamura, Shuzo | Wang, Yin | Veeneman, Brendan | Hovelson, Daniel | Bankhead III, Armand | Broses, Luke J. | Lorenzatti Hiles, Guadalupe | Liebert, Monica | Rubin, John R. | Day, Kathleen C. | Hussain, Maha | Neamati, Nouri | Tomlins, Scott | Palmbos, Philip L. | Grivas, Petros | Day, Mark L.

Body Mass Index, Diet-Related Factors, and Bladder Cancer Prognosis: A Systematic Review and Meta-Analysis
Westhoff, Ellen | Witjes, J. Alfred | Fleshner, Neil E. | Lerner, Seth P. | Shariat, Shahrokh F. | Steineck, Gunnar | Kampman, Ellen | Kiemeney, Lambertus A. | Vrieling, Alina

Disparities in the Use of Continent Urinary Diversions after Radical Cystectomy for Bladder Cancer
Farber, Nicholas J. | Faiena, Izak | Dombrovskiy, Viktor | Tabakin, Alexandra L. | Shinder, Brian | Patel, Rutveej | Elsamra, Sammy E. | Jang, Thomas L. | Singer, Eric A. | Weiss, Robert E.

Defining Priorities to Improve Patient Experience in Non-Muscle Invasive Bladder Cancer
Garg, Tullika | Connors, Jill Nault | Ladd, Ilene G. | Bogaczyk, Tyler L. | Larson, Sharon L.

Challenging Cases in Urothelial Cancer
Soloway, Mark S.

Paper Alert: Molecular Landscape of Non-Muscle Invasive Bladder Cancer
Messing, Edward M.

Clinical Trials Corner
Agarwal, Piyush K. | Sternberg, Cora N.


Most Viewed BLC Articles 2017

Immunotherapy and Radiation – A New Combined Treatment Approach for Bladder Cancer? (Review Article in Vol.1, Iss.1, 2015)
Buchwald, Zachary S. | Efstathiou, Jason A.

Sequential Intravesical Gemcitabine and Docetaxel for the Salvage Treatment of Non-Muscle Invasive Bladder Cancer (Research Article in Vol.1, Iss.1, 2015)
Steinberg, Ryan L. | Thomas, Lewis J. | O’Donnell, Michael A. | Nepple, Kenneth G.

Pelvic Lymph Node Dissection may be Limited on the Contralateral Side in Strictly Unilateral Bladder Cancer without Compromising Oncological Radicality (Research Article in Vol.2, Iss.1, 2016)
Kiss, Bernhard | Paerli, Michael | Schöndorf, Daniel | Burkhard, Fiona C. | Thalmann , George N. | Roth, Beat

Bladder Cancer Molecular Taxonomy: Summary from a Consensus Meeting (Research Article in Vol.2, Iss.1, 2016)
Lerner, Seth P. | McConkey, David J. | Hoadley, Katherine A. | Chan, Keith S. | Kim, William Y. | Radvanyi, François | Höglund, Mattias | Real, Francisco X.

A Systematic Review of the Diagnostic and Prognostic Value of Urinary Protein Biomarkers in Urothelial Bladder Cancer (Research Article in Vol.2, Iss.3, 2016)
D’Costa, Jamie J. | Goldsmith, James C. | Wilson, Jayne S. | Bryan, Richard T. | Ward, Douglas G.


BCAN Research Grants 2018

Submit Your Application!

BCAN raises funds and awards grants to support early career investigators as well as innovative bladder cancer research to develop lifesaving treatments.

Applications are currently open for three Young Investigator Awards (YIA), of $50,000 each, for one year. Deadline for YIA submissions is: Monday, February 26, 2018.

There is also the opportunity to apply for BCAN's 2018 Bladder Cancer Research Innovation Award, which will support the work of one investigator with an exceptionally novel and creative project with great potential to produce breakthroughs in our understanding or the management of bladder cancer. One proposal will be funded for $300,000 over two years ($150,000 per year). Deadline for applicants to submit a letter of intent is: Wednesday, February 21, 2018.

For details about the grant program and application requirements, visit the BCAN website.

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