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Dear Colleague,

We are delighted to announce the publication of Volume 4, Number 2 of Bladder Cancer (BLC). The full contents are freely available online, and can be browsed in full below.

This issue hosts an outstanding selection of articles, including two reviews covering thromboembolism in patients with bladder cancer, and canine invasive urothelial carcinoma as a model to predict the outcomes of targeted therapy and immunotherapy in humans.


Call for Papers

As a member of our research community, we would like to invite you to contribute your own research articles to Bladder Cancer, which offers contributing authors many benefits:

• First class Editorial Board
• Rigorous peer review and speedy manuscript processing
• Rapid online publication (pre-press) on acceptance
• Articles are currently published Open Access with no article processing fee

Submit your manuscript electronically
View detailed Instructions to Authors
Aims and Scope

We look forward to working with you.

Best wishes,


Seth P. Lerner, MD
Scott Department of Urology
Baylor College of Medicine
Houston, Texas, USA

Dan Theodorescu, MD, PhD
University of Colorado Cancer Center
Aurora, Colorado, USA


All articles are freely available to all readers

Review: Thromboembolism in Patients with Bladder Cancer: Incidence, Risk Factors and Prevention
Zareba, Piotr | Duivenvoorden, Wilhelmina C.M. | Pinthus, Jehonathan H.

Review: Naturally-Occurring Canine Invasive Urothelial Carcinoma: A Model for Emerging Therapies
Sommer, Breann C. | Dhawan, Deepika | Ratliff, Timothy L. | Knapp, Deborah W.

Transversus Abdominis Plane Blockade as Part of a Multimodal Postoperative Analgesia Plan in Patients Undergoing Radical Cystectomy
Matulewicz, Richard S. | Patel, Mehul | Jordan, Brian J. | Morano, Jacqueline | Frainey, Brendan | Bhanji, Yasin | Bux, Mahreen | Nader, Antoun | Kundu, Shilajit D. | Meeks, Joshua J.

Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines
Zuiverloon, Tahlita C.M. | de Jong, Florus C. | Costello, James C. | Theodorescu, Dan

The Prognostic Role of the Change in Neutrophil-to-Lymphocyte Ratio During Neoadjuvant Chemotherapy in Patients with Muscle-Invasive Bladder Cancer: A Retrospective, Multi-Institutional Study
Kaiser, Jeenan | Li, Haocheng | North, Scott A. | Leibowitz-Amit, Raya | Seah, Jo-An | Morshed, Nisha | Chau, Caroline | Lee-Ying, Richard | Heng, Daniel Y.C. | Sridhar, Srikala | Crabb, Simon J. | Alimohamed, Nimira S.

Prognostication in Patients Treated with Radical Cystectomy for Urothelial Bladder Carcinoma: A New Simplified Model Incorporating Histological Variants
Ku, Ja Hyeon | Yuk, Hyeong Dong | Godoy, Guiherme | Amiel, Gilard E. | Lerner, Seth P.

The Role of Adjuvant Radiation Therapy in Locally Advanced Bladder Cancer
Lewis, Gary D. | Haque, Waqar | Verma, Vivek | Butler, E. Brian | Teh, Bin S.

Bladder Cancer Genetic Susceptibility. A Systematic Review
de Maturana, Evangelina López | Rava, Marta | Anumudu, Chiaka | Sáez, Olga | Alonso, Dolores | Malats, Núria

Real-World Effectiveness of Chemotherapy in Elderly Patients With Metastatic Bladder Cancer in the United States
Galsky, Matthew D. | Pal, Sumanta Kumar | Lin, Shih-Wen | Ogale, Sarika | Zivkovic, Marko | Simpson, Joseph | Derleth, Christina | Schiff, Christina | Sonpavde, Guru

Challenging Cases in Urothelial Cancer
Soloway, Mark S.

Clinical Trials Corner
Agarwal, Piyush K. | Sternberg, Cora N.

Paper Alert: Molecular Psychological Stress and Suicide in Bladder Cancer Patients
Messing, Edward M.


Most Viewed BLC Articles, January to March 2018

Sequential Intravesical Gemcitabine and Docetaxel for the Salvage Treatment of Non-Muscle Invasive Bladder Cancer (Research Article in Vol.1, Iss.1, 2015)
Steinberg, Ryan L. | Thomas, Lewis J. | O’Donnell, Michael A. | Nepple, Kenneth G.

Immune Responses to Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer (Review Article in Vol.4, Iss.1, 2018)
Sherif, Amir | Winerdal, Malin | Winqvist, Ola

Liquid Biopsy-Analysis of Circulating Tumor DNA (ctDNA) in Bladder Cancer (Review Article in Vol.4, Iss.1, 2018)
Todenhöfer, Tilman | Struss, Werner J. | Seiler, Roland | Wyatt, Alexander William | Black, Peter C.

Bladder Cancer Molecular Taxonomy: Summary from a Consensus Meeting (Research Article in Vol.2, Iss.1, 2016)
Lerner, Seth P. | McConkey, David J. | Hoadley, Katherine A. | Chan, Keith S. | Kim, William Y. | Radvanyi, François | Höglund, Mattias | Real, Francisco X.

Body Mass Index, Diet-Related Factors, and Bladder Cancer Prognosis: A Systematic Review and Meta-Analysis (Research Article in Vol.4, Iss.1, 2018)
Westhoff, Ellen | Witjes, J. Alfred | Fleshner, Neil E. | Lerner, Seth P. | Shariat, Shahrokh F. | Steineck, Gunnar | Kampman, Ellen | Kiemeney, Lambertus A. | Vrieling, Alina



Bladder Cancer Awareness Month Kick Off!

During May 2018, BCAN is running a number of awareness initiatives and raising funds to educate and support bladder cancer patients and research. Andrea Maddox-Smith, BCAN Chief Executive Officer, comments, “We are shining a light on bladder cancer to say we will not be silent. BCAN feels strongly that patients should not learn about bladder cancer for the first time when the doctor provides their diagnosis.”

Read more at the BCAN website.

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