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Volume 69, Issue 1 / 2019 Available Online

Includes the mini-forum "IMI PharmaCog WP5-European ADNI Study: Role of Biomarkers to Diagnose and Track Short Term Disease Progression in Prodromal Alzheimer's Disease"
(Guest Editor: Giovanni B. Frisoni)

Mini-Forum Content

One Step Forward Toward a Surrogate Endpoint for Clinical Trials of Alzheimer’s Disease Drugs: The Results of PharmaCog WP5 (European ADNI)Openly Available (Editorial)
Frisoni, Giovanni B. | Blin, Olivier | Bordet, Regis

Predicting and Tracking Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer’s Disease: Structural Brain Biomarkers
Marizzoni, Moira | Ferrari, Clarissa | Jovicich, Jorge | Albani, Diego | Babiloni, Claudio | Cavaliere, Libera | Didic, Mira | Forloni, Gianluigi | Galluzzi, Samantha | Hoffmann, Karl-Titus | et al.

Two-Year Longitudinal Monitoring of Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer’s Disease Using Topographical Biomarkers Derived from Functional Magnetic Resonance Imaging and Electroencephalographic Activity
Jovicich, Jorge | Babiloni, Claudio | Ferrari, Clarissa | Marizzoni, Moira | Moretti, Davide V. | Del Percio, Claudio | Lizio, Roberta | Lopez, Susanna | Galluzzi, Samantha | Albani, Diego | et al.

Plasma Aβ42 as a Biomarker of Prodromal Alzheimer’s Disease Progression in Patients with Amnestic Mild Cognitive Impairment: Evidence from the PharmaCog/E-ADNI Study
Albani, Diego | Marizzoni, Moira | Ferrari, Clarissa | Fusco, Federica | Boeri, Lucia | Raimondi, Ilaria | Jovicich, Jorge | Babiloni, Claudio | Soricelli, Andrea | Lizio, Roberta | et al.

Regular Issue Content

Review Articles

The Potential Influence of Bone-Derived Modulators on the Progression of Alzheimer’s Disease
Yuan, Jun | Meloni, Bruno P. | Shi, Tianxing | Bonser, Anne | Papadimitriou, John M. | Mastaglia, Frank L. | Zhang, Changqing | Zheng, Minghao | Gao, Junjie

Assessment of Conjunctive Binding in Aging: A Promising Approach for Alzheimer’s Disease Detection
Martínez, Juan F. | Trujillo, Catalina | Arévalo, Analía | Ibáñez, Agustín | Cardona, Juan F.

Research Articles

Plasma Levels of Soluble AβPPβ as a Biomarker for Alzheimer’s Disease with Dementia
Alexopoulos, Panagiotis | Thierjung, Nathalie | Economou, Polychronis | Werle, Lukas | Buhl, Felix | Kagerbauer, Simone | Papanastasiou, Anastasios D. | Grimmer, Timo | et al.

Choroid Plexus Acts as Gatekeeper for TREM2, Abnormal Accumulation of ApoE, and Fibrillary Tau in Alzheimer’s Disease and in Down Syndrome DementiaOpen Access
Raha-Chowdhury, Ruma | Henderson, James W. | Raha, Animesh Alexander | Vuono, Romina | Bickerton, Anastasia | Jones, Elizabeth | Fincham, Robert | Allinson, Kieren | Holland, Anthony | Zaman, Shahid H.

Cardiorespiratory Fitness Modifies Influence of Sleep Problems on Cerebrospinal Fluid Biomarkers in an At-Risk Cohort
Law, Lena L. | Sprecher, Kate E. | Dougherty, Ryan J. | Edwards, Dorothy F. | Koscik, Rebecca L. | Gallagher, Catherine L. | Carlsson, Cynthia M. | Zetterberg, Henrik | Blennow, Kaj | et al.

Genetic Sample Provision Among National Alzheimer’s Coordinating Center Participants
Bardach, Shoshana H. | Jicha, Gregory A. | Karanth, Shama | Zhang, Xuan | Abner, Erin L.

Greater Regional Cortical Thickness is Associated with Selective Vulnerability to Atrophy in Alzheimer’s Disease, Independent of Amyloid Load and APOE Genotype
Li, Chunfei | Duara, Ranjan | Loewenstein, David A. | Izquierdo, Walter | Cabrerizo, Mercedes | Barker, Warren | Adjouadi, Malek | and for the Alzheimer’s Disease Neuroimaging Initiative

Phospho-Tau Changes in the Human CA1 During Alzheimer’s Disease ProgressionOpen Access
Regalado-Reyes, Mamen | Furcila, Diana | Hernández, Félix | Ávila, Jesús | DeFelipe, Javier | León-Espinosa, Gonzalo

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Editor's Choice

Deep Brain Stimulation of the Memory Circuit: Improving Cognition in Alzheimer’s Disease (Review Article)
Posporelis, Sotirios | David, Anthony S. | Ashkan, Keyoumars | Shotbolt, Paul

Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed ActivationOpen Access (Research Article)
Leoutsakos, Jeannie-Marie S. | Yan, Haijuan | Anderson, William S. | Asaad, Wael F. | Baltuch, Gordon | Burke, Anna | Chakravarty, M. Mallar | Drake, Kristen E. | Foote, Kelly D. | et al.

In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer’s DiseaseOpen Access (Research Article)
Schartmann, Elena | Schemmert, Sarah | Niemietz, Nicole | Honold, Dominik | Ziehm, Tamar | Tusche, Markus | Elfgen, Anne | Gering, Ian | Brener, Oleksandr | Shah, Nadim Joni | et al.

Ketogenic Medium Chain Triglycerides Increase Brain Energy Metabolism in Alzheimer’s Disease (Research Article)
Croteau, Etienne | Castellano, Christian-Alexandre | Richard, Marie Anne | Fortier, Mélanie | Nugent, Scott | Lepage, Martin | Duchesne, Simon | Whittingstall, Kevin | et al.

Music and Dementia: Individual Differences in Response to Personalized PlaylistsOpen Access (Research Article)
Garrido, Sandra | Stevens, Catherine J. | Chang, Esther | Dunne, Laura | Perz, Janette

Rapidly Progressive Alzheimer’s Disease in Two Distinct Autopsy Cohorts (Research Article)
Pillai, Jagan A. | Appleby, Brian S. | Safar, Jiri | Leverenz, James B.

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News From Our Sister Journal: JPD

Register Now for Free Parkinson's Webinar

The Journal of Parkinson's Disease (JPD), together with Cure Parkinson's Trust and Parkinson’s Movement, organize quarterly webinars to bring the discussion of specific research topics in PD into the open. For colleagues who have an interest in this field, we share the news that the next free webinar is taking place on June 12, 2019 on the topic “Stem Cells Research in Parkinson's.” The host will be JPD Editor-in-Chief Patrik Brundin (Van Andel Research Institute, USA) and the fellow panelists include Roger Barker (University of Cambridge, UK) and Claire Henchcliffe (Weill Cornell Medical College, USA).

Click here to register for the webinar!

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