| Please feel free to forward to your colleagues and share the news of our journal | Dear Colleague, We are delighted to announce the publication of Volume 6, Issue 3 of Bladder Cancer (BLC). The full issue is freely available online and can be browsed in full below. This issue hosts an outstanding selection of content, including two review articles, seven research articles, two systematic reviews, an article commentary, and a position paper with a consensus guideline from the Genitourinary Medical Oncologists of Canada. From the editors of the regular journal sections, there are also new Challenging Case, Clinical Trials Corner and Paper Alert contributions. All articles are open access and can be viewed via the links below. | As a member of our research community, we would like to invite you to contribute your own research articles to Bladder Cancer, which offers contributing authors many benefits: • First class Editorial Board • Rigorous peer review and speedy manuscript processing • Rapid online publication (pre-press) on acceptance • Articles are currently published Open Access with no article processing fee Submit your manuscript online via Editorial Manager View detailed Instructions to Authors Aims and Scope We look forward to working with you. Best wishes, Editors-in-Chief Seth P. Lerner, MD Scott Department of Urology Baylor College of Medicine Houston, Texas, USA Email: blc@iospress.com Dan Theodorescu, MD, PhD Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center Los Angeles, California, USA Email: blc@iospress.com | All content is currently freely available to all readers Review Articles The Urinary Microbiome and Bladder Cancer: Susceptibility and Immune Responsiveness Andolfi, Ciro | Bloodworth, Jeffrey C. | Papachristos, Apostolos | Sweis, Randy F. Review: Brain Metastases in Bladder Cancer Brenneman, Randall J. | Gay, Hiram A. | Christodouleas, John P. | Sargos, Paul | Arora, Vivek | Fischer-Valuck, Benjamin | Huang, Jiayi | Knoche, Eric | Pachynski, Russell | Picus, Joel | et al. Article Commentary Mutations in Non-Tumoral Human Urothelium: Disease Prelude or Epilogue? Piedrafita, Gabriel | Fernández, Luis C. | Real, Francisco X. Research Articles Mutational Analysis of Field Cancerization in Bladder Cancer Strandgaard, Trine | Nordentoft, Iver | Lamy, Philippe | Christensen, Emil | Thomsen, Mathilde Borg Houlberg | Jensen, Jørgen Bjerggaard | Dyrskjøt, Lars Survival of Patients with Muscle-Invasive Urothelial Cancer of the Bladder with Residual Disease at Time of Cystectomy: A Comparative Survival Analysis of Treatment Modalities in the National Cancer Database Pfail, John L. | Audenet, François | Martini, Alberto | Tomer, Nir | Paranjpe, Ishan | Daza, Jorge | Attalla, Kyrollis | Waingankar, Nikhil | Mehrazin, Reza | Wiklund, Peter | et al. Recurrence in Non-Muscle Invasive Bladder Cancer Patients: External Validation of the EORTC, CUETO and EAU Risk Tables and Towards a Non-Linear Survival Model Lucas, Marit | Jansen, Ilaria | Oddens, Jorg R. | van Leeuwen, Ton G. | Marquering, Henk A. | de Bruin, Daniel M. Establishment of Real-Time Multispectral Imaging for the Detection of Bladder Cancer Using a Preclinical in Vivo Model Meessen, Sabine | Rother, Jan | Zheng, Xi | Eckstein, Markus | Kriegmair, Maximilian C. | Hernandez, David | Grychtol, Bartłomiej | Deliolanis, Nikolaos C. | Bolenz, Christian | Günes, Cagatay Optimizing Sequence of PD-L1 Immune-Checkpoint Inhibitors and Radiation Therapy in Bladder Cancer Tholomier, Côme | Marcq, Gautier | Shinde-Jadhav, Surashri | Ayoub, Mina | Huang, Jia Min | Kool, Ronald | Skowronski, Rodrigo | Brimo, Fadi | Mansure, Jose Joao | Kassouf, Wassim Evaluation of a Novel Cystoscopic Compatible Cryocatheter for the Treatment of Bladder Cancer Baust, John M. | Robilotto, Anthony | Santucci, Kimberly L. | Snyder, Kristi K. | Van Buskirk, Robert G. | Katz, Aaron | Corcoran, Anthony | Baust, John G. Diagnostic Performance of Novel Urine-Based mRNA Tests (Xpert and Urinary Metabolomics Markers Assay) for Bladder Cancer Detection in Patients with Hematuria Elsawy, Amr A. | Awadalla, Amira | Maher, Shaza | Ahmed, Asmaa E. | Youssef, Magdy M. | Abol-Enein, Hassan Systematic Reviews Functional Outcomes After Robotic Radical Cystectomy with Intracorporeal Diversion Daza, Jorge | Jones, Tashzna | Raven, Matthew | Charap, Andrew | Sfakianos, John P | Mehrazin, Reza | Mohamed, Nihal | Wiklund, Peter Radiomics and Bladder Cancer: Current Status Cacciamani, Giovanni E. | Nassiri, Nima | Varghese, Bino | Maas, Marissa | King, Kevin G. | Hwang, Darryl | Abreu, Andre | Gill, Inderbir | Duddalwar, Vinay Position Paper Current Management of Localized Muscle-Invasive Bladder Cancer: A Consensus Guideline from the Genitourinary Medical Oncologists of Canada Jiang, Di Maria | North, Scott A. | Canil, Christina | Kolinsky, Michael | Wood, Lori A. | Gray, Samantha | Eigl, Bernhard J. | Basappa, Naveen S. | Blais, Normand | Winquist, Eric | et al. Other Content Challenging Cases in Urothelial Cancer Soloway, Mark S. Clinical Trials Corner Agarwal, Piyush K. | Sternberg, Cora N. Paper Alert | New Salvage Treatments for Metastatic Bladder Cancer Messing, Edward | Listing articles published only in 2019 & 2020 so you can read the most popular recent content In the World of Bladder Tumors: Size Does Matter (Research Article in Vol.6, Iss.2, 2020) Loloi, Justin | Allen, Jordan L. | Schilling, Amber | Hollenbeak, Christopher | Merrill, Suzanne B. | Kaag, Matthew G. | Raman, Jay D. Clinical Development of FGFR3 Inhibitors for the Treatment of Urothelial Cancer (Review Article in Vol.5, Iss.2, 2019) Ibrahim, Tony | Gizzi, Marco | Bahleda, Ratislav | Loriot, Yohann CIS of the Bladder: Significance and Implications for Therapy (Review Article in Vol.5, Iss.3, 2019) Mirabal, Jorge Rivera | Taylor, John A. | Lerner, Seth P. Genomic Biomarkers and Underlying Mechanism of Benefit from BCG Immunotherapy in Non-Muscle Invasive Bladder Cancer (Research Article in Vol.6, Iss.2, 2020) Bastos, Diogo A. | Mattedi, Romulo L. | Barreiro, Rodrigo | dos Santos, Filipe F. | Buzatto, Vanessa | Masotti, Cibele | Souza, Jussara M. | de Lima, Mariana Z. T. | Friguglietti, Giulia W. | et al. Cisplatin Ineligibility for Patients With Metastatic Urothelial Carcinoma: A Survey of Clinical Practice Perspectives Among US Oncologists (Research Article in Vol.5, Iss.4, 2019) Galsky, Matthew D. | Ma, Esprit | Shah-Manek, Bijal | Mills, Rosalina | Ha, Long | Krebsbach, Craig | Blouin, Eric | Tayama, Darren | Ogale, Sarika Histologic Variants of Urothelial Carcinoma: Morphology, Molecular Features and Clinical Implications (Review Article in Vol.6, Iss.2, 2020) Alderson, Meera | Grivas, Petros | Milowsky, Matthew I. | Wobker, Sara E. | Bladder Cancer Summit for Patients and Families Oct 10, 2020 | Online The Bladder Cancer Summit for Patients and Families takes place this year as an online meeting on Saturday, October 10, 2020 from 13:00 to 17:00 ET. Join this event to: understand how BCAN programs and services can help in their bladder cancer journey; learn about the impact of COVID-19 on bladder cancer treatment; hear leading bladder cancer experts discuss recent and upcoming bladder cancer research advances; and connect with other bladder cancer patients, survivors, and caregivers. Further information and details of the day-long program on the BCAN website here. Virtual Walk to End Bladder Cancer Oct 3, 2020 | Virtual " Walk with Us" at the 2020 Virtual Walk to End Bladder Cancer on Saturday, October 3, 2020 at 11:00 ET as a way to safely connect with friends and family and help end one of the most common cancers. A special broadcast will also take place on the day via BCAN’s Facebook, YouTube, and Twitter channels at 11:00 ET. Join us! More details on the BCAN website here. You are invited to join BCAN for two virtual events in Oct 2020: “Walk with Us, Talk with Us” | Global Congress on Bladder Cancer Oct 15, 2020 | Online This year's Global Congress on Bladder Cancer (BLADDR 2020) will take place virtually and you are guaranteed valuable online interactions with experts in the field, alongside the Global Congress of Prostate Cancer (PROSCA 2020). Presentations will be published online from October 10 onwards and a livestream session will take place on October 15, when you can watch the presentations and learn more about bladder cancer topics with live case discussions and debates. For further information, program details, and registration, visit the event website here. | Help Spread the News of BLC! | If you know of any colleagues or fellow researchers who are not yet signed up to receive the newsletter, we invite you to share this mailing with them. Click on the visual or access the sign-up link here. BLC has an active social media presence. 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